Crystal structure of BCL-XL in complex with a benzothiazole-based inhibitor
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Crystal structure of BCL-XL in complex with a benzothiazole-based inhibitor Descriptor: Bcl-2-like protein 1, N-(1,3-benzothiazol-2-yl)-2-(4-{[(4-{[(2R)-4-(morpholin-4-yl)-1-(phenylsulfanyl)butan-2-yl]amino}-3-[(trifluoromethyl)sulfonyl]phenyl)sulfonyl]carbamoyl}-1,3-thiazol-2-yl)-1,2,3,4-tetrahydroisoquinoline-8-carboxamide Authors: Judge, R.A, Tao, Z. Deposit date: 2021-01-21 Release date: 2021-06-23 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.409 Å) Cite: Structure-Based Design of A-1293102, a Potent and Selective BCL-XL Inhibitor ACS Medicinal Chemistry Letters, 12, 2021
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2021-01-21
