官方服务：
资源简介：
HLA ligand profiles of primary renal cell carcinoma maintained in metastases.sue
应用场景：
创建时间：
2025-01-24
相关数据集
Gene and protein sequence features augment HLA class I ligand predictions (mRNA sequencing)
The sensitivity of malignant tissues to T cell-based cancer immunotherapies is dependent on the presence of targetable HLA class I ligands on the tumor cell surface. Peptide intrinsic factors, such as
NIAID Data Ecosystem100
Memory T cells recognize divergent HLA-DP
We investigated the contribution of naive and memory T cells to alloreactivity against HLA-DP with increasing immunopeptidome divergence and their modulation by HLA-DM.
NIAID Data Ecosystem30
Frequency comparison of the L90M and correlated substitutions
Results of the Fisher exact test of L90M, M46I, A71V, V82A and I84V between B*15+ or B*48+ sets and B*48−/B*15- sequence sets. The calculated odds ratios and associated p-values and q-values are shown
Figshare2015-12-02 更新20
DataSheet_1_Diagnostic Test Criteria for HLA Genotyping to Prevent Drug Hypersensitivity Reactions: A Systematic Review of Actionable HLA Recommendations in CPIC and DPWG Guidelines.docx
IntroductionCertain HLA variants are associated with an increased risk of hypersensitivity reactions to specific drugs. Both the Clinical Pharmacogenetics Implementation Consortium (CPIC) and the Dutc
NIAID Data Ecosystem30
Identification of HLA class I-presented peptides in MSI CRC model cell line HCT-116
HCT-116 cells were treated either with 5 µM of the NMD inhibitor 5-azacytidine (PMID: 25319547) or DMSO (negative solvent control) for 24 h to examine differences in HLA class I-mediated peptide prese
NIAID Data Ecosystem30
