Frequency comparison of the L90M and correlated substitutions

Results of the Fisher exact test of L90M, M46I, A71V, V82A and I84V between B*15+ or B*48+ sets and B*48−/B*15- sequence sets. The calculated odds ratios and associated p-values and q-values are shown. Most of the results show a significant p-values below 0.05 with q-values below 0.1, except for M46I in the B*48+ set which yielded a p-value and q-value of 0.230 and 0.256 respectively.