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Identification of HLA class I-presented peptides in MSI CRC model cell line HCT-116

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NIAID Data Ecosystem2026-03-12 收录
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HCT-116 cells were treated either with 5 µM of the NMD inhibitor 5-azacytidine (PMID: 25319547) or DMSO (negative solvent control) for 24 h to examine differences in HLA class I-mediated peptide presentation. Moreover, data were used for the identification of tumor-specific neoepitopes originating from insertion/deletion mutations due to microsatellite instability.

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2021-04-14
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