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Investigation of plasmid changes in mutants of K. pneumoniae isolate KP1099 by genomic sequencing. Klebsiella pneumoniae

NIAID Data Ecosystem2026-03-10 收录

细菌耐药性机制

质粒基因组分析

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA393721 数据链接链接失效反馈

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资源简介：

The purpose of this study was to explore mechanisms of resistance to meropenem/vaborbactam in clinical isolates of Klebsiella pneumoniae.

应用场景：

创建时间：

2017-07-27

细菌耐药性机制

消毒剂-抗生素交叉耐药

Susceptibility to antibiotics of S. maltophilia benzalkoniumbenzalkonium chloride resistant mutants, and their complemented derivatives.

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Genome assembly of five Staphylococcus aureus strains. Staphylococcus aureus subsp. aureus COL strain:MM25

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In this study, we describe the sequencing and assembly of five methicillin resistant S aureus strains. Four strains were hospital acquired clinically isolated from a hospital in southern New Mexico. O

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This study shows that S. aureus is more versatile than recently concluded. First, mutants selected on the FabI inhibitor triclosan are about 100-fold more frequent when fatty acids are available. A novel FASII bypass target is identified as FabD, a malonyl CoA-acyl carrier protein transacylase.

细菌耐药性机制

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Antimicrobials targeting the fatty acid synthesis pathway (FASII) may be bypassed by numerous pathogens that incorporate host fatty acids. This activity would greatly restrict use of anti-FASII drugs.

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Table_4_Genome-Wide Association Studies for the Detection of Genetic Variants Associated With Daptomycin and Ceftaroline Resistance in Staphylococcus aureus.xlsx

抗生素耐药性GWAS

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BackgroundAs next generation sequencing (NGS) technologies have experienced a rapid development over the last decade, the investigation of the bacterial genetic architecture reveals a high potential t

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Comparative genomics and transcriptomics to identify genetic mechanisms underlying the emergence of carbapenem resistant Acinetobacter baumannii (CRAb). Acinetobacter baumannii 466760

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Comparative genomics and transcriptomics to identify genetic mechanisms underlying the emergence of carbapenem resistant Acinetobacter baumannii (CRAb)

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Investigation of plasmid changes in mutants of K. pneumoniae isolate KP1099 by genomic sequencing. Klebsiella pneumoniae

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