The impact of eosinophils on the in vitro differentiation of osteoclasts. The impact of eosinophils on the in vitro differentiation of osteoclasts

To investigate the role of eosinophils on osteoclast differentiation from bone marrow-derived monocytes (BMMs), BMMs were cultivated in the presence or absence of eosinophils and eosinophil supernatant as compared with unstimulated control. Overall design: The mRNA expressional changes in osteoclasts upon stimulation with eosinophils or eosinophil supernatant were anlaysed by bulk RNA sequencing