首页/数据集/Acute depletion of Tet1-dependent 5-hydroxymethylcytosine levels impairs LIF/Stat3 signaling and results in loss of embryonic stem cell identity

Acute depletion of Tet1-dependent 5-hydroxymethylcytosine levels impairs LIF/Stat3 signaling and results in loss of embryonic stem cell identity

NIAID Data Ecosystem2026-03-11 收录

胚胎干细胞调控

STAT3信号通路

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE34267 数据链接链接失效反馈

官方服务：

资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

应用场景：

创建时间：

2019-05-15

免疫耐受调节

STAT3信号通路

Dendritic cell (DC) fine-tunes inflammatory versus tolerogenic responses to protect from immune-pathology. However, the role of co-regulators in maintaining this balance is unexplored. NCoR1-mediated

NIAID Data Ecosystem50

Additional file 4: of Codon usage optimization in pluripotent embryonic stem cells

胚胎干细胞调控

密码子使用偏好分析

Table S3. Distribution of hetADAT targets at ribosome covered codons in (a) differentiated versus self-renewing hESCs. The A-site is highlighted in yellow and (b) differentiated embryoid bodies (EB) v

Figshare2019-06-08 更新50

CDYL2 epigenetically regulates MIR124 to control NF-kB/STAT3-dependent breast cancer cell plasticity [RNA-seq]

乳腺癌细胞可塑性

STAT3信号通路

Epigenetic deregulation of gene transcription is central to cancer cell plasticity and malignant progression, but remains poorly understood. We found that the uncharacterized epigenetic factor Chromod

NIAID Data Ecosystem30

Resistance to Spindle inhibitors in Glioblastoma Depends on STAT3 and Therapy Induced Senescence. Resistance to Spindle inhibitors in Glioblastoma Depends on STAT3 and Therapy Induced Senescence

胶质母细胞瘤耐药性

STAT3信号通路

While mitotic spindle inhibitors specifically kill proliferating tumor cells without the toxicities of microtubule poisons, resistance has limited their clinical utility. Treating glioblastomas with t

NIAID Data Ecosystem50

fig. 7

STAT3信号通路

辐射诱导细胞损伤

Inhibition of proliferation and promotion of apoptosis and DNA damage by the targeting of STAT3 by miR-125a-5p in irradiated mouse intestinal epithelial cells.

NIAID Data Ecosystem30

Acute depletion of Tet1-dependent 5-hydroxymethylcytosine levels impairs LIF/Stat3 signaling and results in loss of embryonic stem cell identity

资源简介：

相关数据集