The calculated successful target rate is reported for each sample as an index of the number of successful binding events between probe and target molecule. This quantity was calculated as the percenta

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Mean association and dissociation kinetic rate constants (k on , k off ) and equilibrium dissociation constants (KD), calculated from surface plasmon resonance (SPR) measurements for aqueous Mini-B (MB) and Super Mini-B (S-MB) flowing past chip-linked Cys-MB and Cys-S-MB monolayer

分子相互作用

表面等离子体共振分析

aMB and S-MB in running buffer (10 mM HEPES, 150 mM NaCl, 3 mM EDTA, 0.005% Surfactant P20, pH 7.4) were flowed past monolayers of N-terminal Cys-MB or N-terminal Cys-S-MB, linked via their respective

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Kinetics of lucanthone and hycanthone binding to APE1.

药物靶点结合动力学

表面等离子体共振分析

Hycanthone shows higher binding affinity as compared to Lucanthone. Data in Table 1 show affinity analysis of lucanthone (LUC) and hycanthone (HYC) binding to APE1 immobilized on CM5 chip (Figure 6A a

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Data obtained from the analysis of the SPR injections of ethanol.

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