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Memory T cell receptor sequencing from human bone marrow and lymph nodes

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NIAID Data Ecosystem2026-03-12 收录
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The goal of this study was to profile human memory T cells isolated from lymphoid tissues including bone marrow and lymph nodes from organ donors. Here, we seek to understand tissue-specific features of CD4+ and CD8+ T cells including their clonal T cell repertoires. We conducted T cell receptor sequencing of memory T cells isolated from lymph nodes and bone marrow. The publication associated with this data can be found here, with included methods describing how this data was generated : J Immunol August 15, 2018, ji1800716; DOI: https://doi.org/10.4049/jimmunol.1800716. Title: Human Lymph Nodes Maintain TCF-1hi Memory T Cells with High Functional Potential and Clonal Diversity throughout Life.

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2020-09-05
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