首页/数据集/Biomarkers Associating with PARP Inhibitor Benefit in Prostate Cancer in the TOPARP-B Trial. Biomarkers Associating with PARP Inhibitor Benefit in Prostate Cancer in the TOPARP-B Trial

Biomarkers Associating with PARP Inhibitor Benefit in Prostate Cancer in the TOPARP-B Trial. Biomarkers Associating with PARP Inhibitor Benefit in Prostate Cancer in the TOPARP-B Trial

NIAID Data Ecosystem2026-03-12 收录

前列腺癌精准治疗

帕普抑制研究

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJEB45010 数据链接链接失效反馈

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资源简介：

Biomarkers Associating with PARP Inhibitor Benefit in Prostate Cancer in the TOPARP-B Trial

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创建时间：

2021-07-17

卵巢癌耐药性

帕普抑制研究

Cancer-associated fibroblasts (CAFs) play significant roles in drug resistance through different ways. Antitumor therapies, including molecular targeted interventions, not only effect tumor cells but

NIAID Data Ecosystem40

Tankyrase 2 in complex with an inhibitor (OUL228)

蛋白质复合物结构解析

帕普抑制研究

Tankyrase 2 in complex with an inhibitor (OUL228) Descriptor: 8-propan-2-yloxy-4~{H}-thieno[2,3-c]isoquinolin-5-one, GLYCEROL, Poly [ADP-ribose] polymerase tankyrase-2, ... Authors: Sowa, S.T, Lehtio,

Protein Data Bank Japan2024-01-31 更新30

Metadata record for the manuscript: Olaparib for Metastatic Breast Cancer in a Patient with a Germline PALB2 Variant

乳腺癌转移治疗

帕普抑制研究

Summary This metadata record provides details of the data supporting the claims of the related manuscript. The related study reports a patient with germline/somatic BRCA1/2 wild-type metastatic breast

NIAID Data Ecosystem20

Depletion of PARP-2 in C2C12 cells. Depletion of PARP-2 in C2C12 cells

帕普抑制研究

骨骼肌代谢

Poly(ADP-ribose) polymerase-2 (PARP-2) is acknowledged as a DNA repair enzyme; however, recently metabolic properties had been attributed to it. Hereby, we examined the metabolic consequences of PARP-

NIAID Data Ecosystem30

DataSheet_1_Clinical, Radiometabolic and Immunologic Effects of Olaparib in Locally Advanced Triple Negative Breast Cancer: The OLTRE Window of Opportunity Trial.pdf

三阴性乳腺癌治疗

帕普抑制研究

IntroductionOlaparib is effective in metastatic triple negative breast cancer (TNBC) carrying germline mutations in DNA damage repair (DDR) genes BRCA1/2 (gBRCA-mut). The OLTRE window-of-opportunity t

NIAID Data Ecosystem20

Biomarkers Associating with PARP Inhibitor Benefit in Prostate Cancer in the TOPARP-B Trial. Biomarkers Associating with PARP Inhibitor Benefit in Prostate Cancer in the TOPARP-B Trial

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