To investigate the effect of miR-503 in aging associated type 2 diabetes, target genes of miR-503 need to be investigated. The global miR-322-503-351 deletion (KO) mouse was constructed, and RNA-seq w
The study aim was to investigate the effect of endogenous insulin release on lipolysis in subcutaneous adipose tissue after adrenergic stimulation in obese subjects diagnosed with type 2 diabetes (T2D
Polycystic ovary syndrome (PCOS) is a common gynecological endocrine disease and was reported to be affected by the gut microbiome dysbiosis. We recruited treatment-naïve PCOS patients and hormonally
Skeletal myocytes are metabolically active and susceptible to insulin resistance, thus implicated in type 2 diabetes (T2D). This complex disease involves systemic metabolic changes and their elucidati
we collected 290 stool samples from a previous reported Chinese cohort , followed by shotgun metagenomics and metaproteomics analyses. Here, we characterized substantial alterations of the intestinal
