Gene expresssion analysis in liver and white adipose tissues from miR-322-503-351 knock out mice.

To investigate the effect of miR-503 in aging associated type 2 diabetes, target genes of miR-503 need to be investigated. The global miR-322-503-351 deletion (KO) mouse was constructed, and RNA-seq was then performed on aged mouse liver and white adipose tissue (WAT). We then performed gene expression profiling analysis using data obtained from RNA-seq of liver and WAT from 52-week-old WT and KO mice.