AA: Alternative Allele; the allele associated with a decrease in the phenotype; BMI: Body Mass Index; Chr.: Chromosome; Overweight: BMI ≥23 kg/m2; compared to normal weight; Position: From build 36.1;
Two genetic simulation models are assumed: neutral variants (1), and mildly deleterious variants (2). Varying number of DSVs are assumed, that can contribute equally or unequally to the total PAR. The
Data are presented as mean, SEM, n stratified by genotype for each of the three SNPs. For each genotype the risk allele was defined as the BMI-increasing allele and the data are presented as the addit