Samoyeds and Australian Terriers are the 2 dog breeds at highest risk (>10-fold) for diabetes mellitus in the United States. It is unknown if the insulin (INS) gene is involved in the pathophysiolo
Each model is fitted with response variable reactor status (0 = positive test, 1 = negative test) and group (either breed, ‘B’, or STRUCTURE group, ‘S’, fitted as a factor) and genotype (‘G’, fitted a
AA: Alternative Allele; the allele associated with a decrease in the phenotype; BMI: Body Mass Index; Chr.: Chromosome; Overweight: BMI ≥23 kg/m2; compared to normal weight; Position: From build 36.1;
Data are presented as mean, SEM, n stratified by genotype for each of the three SNPs. For each genotype the risk allele was defined as the BMI-increasing allele and the data are presented as the addit