Chemical-based external stimulation reprograms BJs into FiNs (scATAC-seq)

Here, we report that chemical-based external stimulation reprograms human BJs to generate human induced FiNs. Using transcriptome,and chromatin accessibility, we identified the cells exhibited key features of FiNs in transcriptomic profiles, epigenetic status. In addition, we also analyzed the reprogramming process. Overall design: Cells at the end of 0 day,3 day were analyzed by ATAC-seq.