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Paneth cells acquire multi-potency upon Notch activation after irradiation

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干细胞与再生医学数据中心2022-02-20 更新2024-03-06 收录
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In murine models, we find that irradiation of Paneth cells caused a gain of a stem cell-like transcriptome and induced activation of the Notch signaling pathway. This study documents plasticity by Paneth cells, a fully committed cell population to participate in epithelial replenishment following stem cell loss.

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2022-02-20
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