Crystal structure of human CYP3A4 bound to an inhibitor
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Crystal structure of human CYP3A4 bound to an inhibitor Descriptor: Cytochrome P450 3A4, PROTOPORPHYRIN IX CONTAINING FE, tert-butyl [(2S)-1-{[(2R)-3-oxo-2-[(propan-2-yl)amino]-3-{[(pyridin-3-yl)methyl]amino}propyl]sulfanyl}-3-phenylpropan-2-yl]carbamate Authors: Sevrioukova, I. Deposit date: 2017-10-21 Release date: 2017-12-13 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.42 Å) Cite: Interaction of the rationally designed ritonavir-like inhibitors with human cytochrome P450 3A4: Impact of the side group interplay Mol. Pharm., 2017
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2017-10-21
