Background: Carfilzomib improves the prognosis of multiple myeloma (MM) patients but significantly increases cardiovascular toxicity. The timing and effect of Carfilzomib therapy on the left ventricul
Functional oncogenic links between ErbB2 and ERR⍺ in HER2+ breast cancer patients support a therapeutic benefit of co-targeted therapies. However, ErbB2 and ERR⍺ also play key roles in heart physiolog
To examine the role of the TGF-beta/Smad3 pathway in cardiac damage by doxorubicin, we performed comparitive RNA sequencing analysis of human cardiac endothelial cells transfected with Smad3 shRNA O
Adolescent and young adult patients aged 15 to 39 years with a diagnosis of sarcoma who were scheduled to receive high-dose Dox (≥300 mg/m²) at a single tertiary cancer center between 2018 and 2022 we
Statistical analyses. (A) Correlations Spearman tests between the fold change of cTnT, NT-proBNP, sST2, miR-126-3p, miR-199a-3p, miR-423-5p and miR-34a-5p at different time point of the neoadjuvant ch