Effect of TGFB1 and Smad3 deficiency on doxorubicin cardiotoxity
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资源简介：
To examine the role of the TGF-beta/Smad3 pathway in cardiac damage by doxorubicin, we performed comparitive RNA sequencing analysis of human cardiac endothelial cells transfected with Smad3 shRNA Overall design: To determine if the endothelial response to TGF-beta1 was enhanced by pretreatment with doxorubicin, human cardiac endothelial cells were pretreated with doxorubicin and subsequently exposed to TGF-beta1 to examine activation of the canonical pathway.
创建时间：
2022-10-16
