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Gene expression profile of macrophages in aneurysm lesions at the growth phase.

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NIAID Data Ecosystem2026-03-14 收录
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Recent experimental studies have defined intracranial aneurysms as a macrophage-mediated chronic inflammatory disease affecting intracranial arteries. We used single cell RNA sequencing (scRNA-seq) to analyze the population of macrophages in aneurysm lesions at the growth phase. Overall design: The previously-established aneurysm model of rats was used. Macrophages were labeled with the fluorescent protein and isolated by a laser-microdissection method and analyzed using scRNAseq.

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2023-01-31
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