Role of macrophages in colitis

NIAID Data Ecosystem2026-03-11 收录

结肠炎机制

巨噬细胞基因表达

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE68269 数据链接链接失效反馈

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The goal of this project is to identify genes preferentially expressed in inflammatory macrophages as compared with control macrophages. inflammatory macrophage vs. control macrophage

创建时间：

2019-03-04

BMI1 Maintains the Regulatory T cell Epigenomic Landscape to Prevent Inflammatory Bowel Disease (Microarray). BMI1 Maintains the Regulatory T cell Epigenomic Landscape to Prevent Inflammatory Bowel Disease (Microarray)

免疫表观遗传学

结肠炎机制

FOXP3+ Treg cells are expanded within the inflamed intestine of human Crohn’s disease, yet FOXP3-mediated gene repression within these cells is lost. The Polycomb repressive complexes play a role in F

NIAID Data Ecosystem20

Analysis of the role of microbiota in macrophages using single cell RNA sequencing (scRNA-seq).. Analysis of the role of microbiota in macrophages using single cell RNA sequencing (scRNA-seq).

肠道微生物-免疫互作

结肠炎机制

Single-cell sequencing of intestinal macrophage was peformed with mice colony stimulating factor 1 receptor promoter (CSF1R) positive cells isolated from the 1/3 distal part of the small intestine of

NIAID Data Ecosystem10

Additional file 1 of Elevated levels of butyric acid in the jejunum of an animal model of broiler chickens: from early onset of Clostridium perfringens infection to clinical disease of necrotic enteritis

家禽代谢组学

结肠炎机制

Supplementary Material 1: Table S1 Composition of feed used in the study. Table S2 Metabolite ratios determined across different NE birds. Table S3 34 differentially expressed metabolites across diffe

NIAID Data Ecosystem00

The kinase DYRK1A reciprocally regulates the differentiation of Th17 and regulatory T cells [seq]

细胞分化调控

结肠炎机制

Using an unbiased chemical biology approach, we discover harmine as a novel regulator of Treg/Th17 differentiation. Harmine enhances Treg differentiation (working in conjunction with low levels of exo

NIAID Data Ecosystem20

hnRNPI Gut Microbiota Dysbiosis_Supplemental Figures and Tables

肠道菌群失调

结肠炎机制

This study identifies P. bifermentans and Dubosiella sp. as potential gut microbiota signatures in hnRNPI KO mice. KO mice were more susceptible to exacerbated colitis during the DSS challenge. Additi

NIAID Data Ecosystem00

Role of macrophages in colitis

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