Transcriptional Profiling of Neuronal APP/APLP2 Double-Conditional Knockout Mice

Gene expression analysis of 2-month-old APP/APLP2 double-conditional Knockout (N-dCKO) mice and littermate APLP2 knockout controls, APP knockout and wildtype controls. Mouse hippocampus were dissected for RNA extraction and hybridization on Affymetrix microarrays.本数据集针对2月龄的APP/APLP2双条件性敲除（N-dCKO）小鼠，以及其同窝出生的APLP2单敲除对照组、APP单敲除对照组与野生型对照组开展基因表达分析。研究人员对各组小鼠的海马组织进行解剖分离，随后开展RNA提取，并在Affymetrix基因芯片上完成杂交实验。