Chemical Proteomics Profiling with an Indole Isocyanide Photoprobe

Name: Chemical Proteomics Profiling with an Indole Isocyanide Photoprobe
Creator: Zhengzhou University
Published: 2026-03-20T11:12:47+08:00

integrated proteome resources2026-03-21 收录

化学蛋白质组学

光亲和探针

数据链接：

https://www.iprox.cn/page/project.html?id=IPX0016292000 数据链接链接失效反馈

官方服务：

资源简介：

Chemical Proteomics Profiling with an Indole Isocyanide Photoprobe

提供机构：

Zhengzhou University

创建时间：

2026-03-20

Mapping in vivo target interaction profiles of covalent inhibitors using chemical proteomics with label-free quantification

共价抑制剂靶点分析

化学蛋白质组学

Activity-based protein profiling (ABPP) has emerged as a valuable chemical proteomics method to guide the therapeutic development of covalent drugs by assessing their on-target engagement and off-targ

NIAID Data Ecosystem130

TMT10_hela-ip-buf-pal_1_4_acid_ms3_140min.raw

化学蛋白质组学

药物靶点鉴定

hela treated with DMSO, Bufalin-photoaffinity probe, and Bufalin-photoaffinity probe competed with bufalin

NIAID Data Ecosystem50

Supplementary Table 1 from Quantitative Chemical Proteomics Profiling Differentiates Erlotinib from Gefitinib in EGFR Wild-Type Non–Small Cell Lung Carcinoma Cell Lines

化学蛋白质组学

分子靶向药物

XLSX file - 144K, Protein identifications in eluted fractions from erlotinib-Sepharose and gefitinib-Sepharose

Figshare2013-04-01 更新20

Chemoproteomic selectivity profiling of PIKK and PI3K kinase inhibitors

化学蛋白质组学

激酶抑制剂选择性分析

"Here, we report the development of a novel version of Kinobeads that extends kinome coverage to PIKK and PI3K kinases. This is achieved by inclusion of two affinity probes derived from the clinical P

NIAID Data Ecosystem60

The non-canonical PARP1 inhibitor target, PARP16, contributes to talazoparib polypharmacology and synergy with WEE1 inhibitors: Chemical Proteomics Cal51

癌症靶向治疗

化学蛋白质组学

PARP1 inhibitors (PARP1is) display single-agent anticancer activity in small cell lung cancer (SCLC) and other neuroendocrine tumors independent of BRCA1/2 mutations. Here, we determined the different

NIAID Data Ecosystem40

Chemical Proteomics Profiling with an Indole Isocyanide Photoprobe

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