RNA editing is phenomenon that occurs in both protein coding and non-coding RNAs. Increasing evidence have shown that adenosine-to-inosine RNA editing can potentially rendering substantial functional
CREB and CRTC2 ChIPseq analysis in LKB1-deficient and LKB1-reconstituted A549 NSCLC cells A549 cells expressing the pBabe vector or full length LKB1 were cultured and ChIPseq for CRTC2 and CREB was pe
The usage of expressed somatic mutations may have a unique advantage in identifying active cancer driver mutations. However, accurately calling mutations from RNA-seq data is difficult due to confound
The landscape of somatic copy-number alterations (SCNAs) affecting long non-coding RNAs (lncRNAs) in human cancer remains largely unexplored. While the majority of lncRNAs remains to be functionally c
In this study, we performed whole-exome sequencing (WES) on 33 tissue samples from 6 esophageal cancer patients with lymph node metastasis, compared the differences of the genomic map and evolutionary
