Structure of AcrIIA7 complexed with 1',2'-cADPR and cGG

Structure of AcrIIA7 complexed with 1',2'-cADPR and cGG Descriptor: (1S,3R,4R,6R,9S,11R,14R,15S,16R,18R)-4-(6-amino-9H-purin-9-yl)-9,11,15,16,18-pentahydroxy-2,5,8,10,12,17-hexaoxa-9lambda~5~,11lambda~5~-diphosphatricyclo[12.2.1.1~3,6~]octadecane-9,11-dione, 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), Inhibitor of Type II CRISPR-Cas system Authors: Xiao, Y, Feng, Y. Deposit date: 2023-08-04 Release date: 2024-08-07 Last modified: 2024-12-04 Method: X-RAY DIFFRACTION (2.28 Å) Cite: Single phage proteins sequester signals from TIR and cGAS-like enzymes. Nature, 635, 2024