In this study, we performed whole-exome sequencing (WES) on 33 tissue samples from 6 esophageal cancer patients with lymph node metastasis, compared the differences of the genomic map and evolutionary
Single cell transcriptome analyses of mouse and human model systems of bladder cancer Overall design: OHBBN-induced mouse bladder tumors were dissociated to the single cell level and separated into to
We subject multiple versions and single cell-derived sublines of an archetypal non-small cell lung cancer cell line to experimental scrutiny at the genomic, transcriptomic, and cell population levels.
ChIP-seq, ATAC-seq and RNA-seq analyses were integrated to define direct, transcriptional Tgfβ targets in quiescent tumor propogating cells Overall design: Differential gene expression analyses were p
