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NANOG amplifies STAT3 activation and they synergistically induce the naïve pluripotent program

ChEBI2014-01-06 更新2026-07-21 收录

干细胞多能性调控

转录因子协同作用

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-53529 数据链接链接失效反馈

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NANOG amplifies STAT3 activation and they synergistically induce the naïve pluripotent program

应用场景：

创建时间：

2014-01-06

干细胞多能性调控

非编码RNA功能

Table S1. Summary of primer sequences for quantitative real-time PCR in this study. (XLSX 12 kb)

DataCite Commons2024-02-14 更新130

RNA-Seq after knockdown of the core pluripotency transcription factors OCT4, SOX2, and NANOG in TE03 (I3) human embryonic stem cells (hESCs). RNA-Seq after knockdown of the core pluripotency transcription factors OCT4, SOX2, and NANOG in TE03 human embryonic stem cells (hESCs)

干细胞多能性调控

转录后基因表达分析

The OCT4, NANOG and SOX2 transcription factors (TFs) are at the core of the pluripotency program, activating the expression of pluripotency genes and repressing lineage-specific genes, many of which a

NIAID Data Ecosystem30

NANOGP1, a tandem duplicate of NANOG, exhibits partial functional conservation in human naïve pluripotent stem cells

干细胞多能性调控

基因进化与功能研究

Gene duplication events are important drivers of evolution by providing genetic material for new gene functions. They also create opportunities for diverse developmental strategies to emerge between s

NIAID Data Ecosystem10

AMPK signaling for naïve pluripotency. AMPK signaling for naïve pluripotency

干细胞多能性调控

AMPK信号通路

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

NIAID Data Ecosystem50

AMPK signaling for naÃ¯ve pluripotency [Mm]

干细胞多能性调控

AMPK信号通路

We show activation of AMP kinase (AMPK) with single chemical compounds can endow naÃ¯ve pluripotency. AMPK activators reverted early-stage differentiating cells or epi-stem cells to naÃ¯ve state. More

NIAID Data Ecosystem10

NANOG amplifies STAT3 activation and they synergistically induce the naïve pluripotent program

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