AMPK signaling for naïve pluripotency [Mm]
收藏NIAID Data Ecosystem2026-05-26 收录
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资源简介：
We show activation of AMP kinase (AMPK) with single chemical compounds can endow naïve pluripotency. AMPK activators reverted early-stage differentiating cells or epi-stem cells to naïve state. Moreover, AMPK activators reverted human ESCs to naïve state with pluripotent gene expression profiles and X-chromosome reactivation. Overall design: We analyzed gene expression profiles of mESCs with AICAR during differentiation and reversion
创建时间：
2019-03-31
