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Single-cell sequencing of Klinefelter testicular biopsies

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NIAID Data Ecosystem2026-03-11 收录
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We have evaluated the transcriptome of different testicular cell types, including germ cells, at single cell level in a testicular biopsy of a man with Klinefelter syndrome (XXY karyotype) A testicular biopsy was enzymatically digested and single-cell RNAseq libraries were obtained using 10X genomics platform (10x Genomics Chromium Single Cell Reagent Kit v2). The libraries were sequenced on a NovaSeq600 sequencer (Illumina) using 2x150 bp paired-end sequencing.

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2019-09-02
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