New 4-Spiroannulated Tetrahydroisoquinolines by a One-Pot Sequential Procedure. Isolation and Characterization of σ-Alkylpalladium Heck Intermediates
收藏NIAID Data Ecosystem2026-03-06 收录
数据链接：
官方服务：
资源简介：
A simple and efficient entry to new tetrahydroisoquinolines 4-spiroannulated to a five-membered heterocyclic ring has been achieved starting from secondary N-allylamines and involving sequential 2-iodobenzylation/intramolecular Heck reaction/1,3-dipolar cycloaddition. A variety of Heck cyclization conditions were surveyed. When using Pd(PPh3)4 as catalyst, stable σ-alkylpalladium iodide complexes were isolated and characterizated.
创建时间：
2006-09-28
