New 1,2-dithioether based 2D copper(I) coordination polymer: from synthesis to catalytic application in A³-coupling reaction

A new 2D copper(I) coordination polymeric complex has been synthesized from CuI and 1-(1-{4-chlorophenylthio}propan-2-ylthio)-4-chlorobenzene ([(CuI)₂{ArSCH₂CH(CH₃)SAr}₂]_n, Ar = 4-ClC₆H₄) and characterized by high resolution mass spectrometry (HRMS) and single crystal X-ray diffraction techniques. The complex has been employed as a suitable catalyst for a solvent-free, one-pot, three-component A³-coupling reaction. A variety of aromatic and aliphatic aldehydes, terminal alkynes and aliphatic cyclic secondary amines have been used to prepare a library of propargylamines using the 2D-Cu complex at significantly low concentration (0.2 mol%).本研究以碘化亚铜（CuI）与1-(1-{4-氯苯硫基}丙-2-基硫基)-4-氯苯为原料，合成了一种新型二维一价铜配位聚合物配合物，其分子式为[(CuI)₂{ArSCH₂CH(CH₃)SAr}₂]ₙ（Ar = 4-ClC₆H₄）；通过高分辨质谱（HRMS）与单晶X射线衍射技术对该配合物完成了结构表征。该二维铜配合物可用作无溶剂、一锅法三组分A³-偶联反应的适宜催化剂。以该配合物为催化剂，在催化剂负载量仅为0.2 mol%的极低浓度下，以多种芳香醛、脂肪醛、末端炔烃及脂环族仲胺为底物，成功构建了炔丙胺类化合物的化合物库。