MOESM4 of DamID profiling of dynamic Polycomb-binding sites in Drosophila imaginal disc development and tumorigenesis

Additional file 4: Table S1. Genes in Group I-IV; List of genes with number of GATC fragments within the presumptive regulatory region (2.5 kb upstream to 1.5 kb downstream of the transcriptional start sites (TSS)) displaying transitions between Pc-binding states (gain, loss or no-change transition between enriched, intermediate and depleted HMM states) in scrib1 if compared to WT profiles, and changes in gene expression levels of the respective gene in scrib1 to whose TSS the taGATC fragments had been mapped to. Group I (RNA – up regulated; Pc binding – gain); group II (RNA – down regulated; Pc binding – gain); group III (RNA – up regulated; Pc binding – loss); group IV (RNA – down regulated; Pc binding – loss); m1 (RNA – down regulated; Pc binding – loss and gain); m2 (RNA – up regulated; Pc binding – loss and gain).附加文件4：表S1。第I至IV组基因列表；本列表收录的基因需满足以下条件：在其推定调控区（即转录起始位点（transcriptional start sites, TSS）上游2.5 kb至下游1.5 kb范围内）存在GATC片段，且在scrib1样本中与野生型（Wild Type, WT）对照谱相比，其Pc结合状态发生了转变（即在富集、中间和缺失三种隐马尔可夫模型（Hidden Markov Model, HMM）状态间出现获得、丢失或无变化的转变）；同时，taGATC片段已被定位至这些基因的TSS区域，且对应基因在scrib1样本中的基因表达水平存在变化。分组详情如下：I组（RNA表达上调；Pc结合状态获得）；II组（RNA表达下调；Pc结合状态获得）；III组（RNA表达上调；Pc结合状态丢失）；IV组（RNA表达下调；Pc结合状态丢失）；m1组（RNA表达下调；Pc结合状态同时发生丢失与获得）；m2组（RNA表达上调；Pc结合状态同时发生丢失与获得）。