RNA seq of two independent kidney cancer orthotopic patient-derived xenograft models (RenPDOX-13 & RenPDOX-50) that show differential proinvasive response to antiangiogenics Overall design: RNA sequen
With the advent of potent second-line anti-androgen therapy, we and others have observed an increased incidence of androgen receptor (AR)-null small cell or neuroendocrine prostate cancer (SCNPC) in m
RATIONALE: EMD 121974 may stop the growth of cancer by stopping blood flow to the tumor. PURPOSE: Phase I trial to study the effectiveness of EMD 121974 in treating patients who have locally advanced
This study is being carried out to assess if adding ZD6474 to best supportive care (BSC) is more effective than best supportive care alone, for the treatment of patients with non-small cell lung can
T-bet is a key transcription factor for T helper 1 lineage and overexpression of T-bet inhibited the development of collagen-induced arthritis, a murine model of rheumatoid arthritis. The aim of this