<b>Effect</b><b>s</b><b>of Maternal-</b><b>I</b><b>solated Oligohydramnios on Blood Metabolic Profile in Full-</b><b>T</b><b>erm Singleton Neonates: A Retrospective </b><b>O</b><b>bservational Study</b>

Blood metabolites of 60 neonates with maternal IO and 60 normal controls admitted to The Sixth Affiliated Hospital, Sun Yat-sen University, were analyzed using liquid chromatography-mass spectrometry to identify differential metabolites. Pathway analysis was performed to identify the most enriched metabolic pathways. The discriminant metabolites were further verified in an independent set consisting of 50 neonates with maternal IO and 60 normal controls admitted to The Maternal and Child Health Care Hospital of Huadu.本数据集针对中山大学附属第六医院收治的60例母亲罹患宫内梗阻（maternal IO）的新生儿与60例正常对照新生儿的血液代谢物，采用液相色谱-质谱联用（liquid chromatography-mass spectrometry, LC-MS）技术进行分析，以筛选差异代谢物。随后开展代谢通路富集分析，以确定富集程度最高的代谢通路。研究团队还在独立验证队列中对筛选得到的判别代谢物进行了验证，该验证队列纳入了广州市花都区妇幼保健院收治的50例母亲罹患宫内梗阻的新生儿及60例正常对照新生儿。