Supplementary File S12 from Restoration of the Tumor Suppressor Function of Y220C-Mutant p53 by Rezatapopt, a Small-Molecule Reactivator

The restoration of the p53 signaling pathway in vivo was assessed via p53 pathway profiling analysis in NUGC-3 xenografted tumors after 6 days of 100-mg/kg PC14586 administration.本研究通过对经100mg/kg剂量PC14586给药6天后的NUGC-3异种移植瘤实施p53通路谱分析，以此评估体内p53信号通路（p53 signaling pathway）的恢复情况。