Sensitivity and specificity of adipokines and clinical parameters for T2D among obese.

Logistic regression analysis: Sensitivity, specificity and prediction accuracy for T2D in 141 obese individuals. Model 1 includes all 20 adipokines, whereas model 2 represents parameters with the strongest predictive value for T2D identified by Wald backwards stepwise test. All models are adjusted for BMI, age and gender.Abbreviations: BMI. body mass index; FPG, fasting plasma glucose; HOMA_IR, Homeostatic Model Assessment; ANGPTL 6, angiopoietin-like protein 6; DLK1, preadipocyte factor 1; Nampt, nicotinamide phosphoribosyltransferase (visfatin).逻辑回归分析：141名肥胖个体中2型糖尿病（Type 2 Diabetes, T2D）的灵敏度、特异度与预测准确率。模型1纳入全部20种脂肪因子，模型2则包含经Wald向后逐步检验筛选出的对2型糖尿病预测价值最强的参数。所有模型均针对身体质量指数（Body Mass Index, BMI）、年龄及性别进行校正。 缩写说明：BMI：身体质量指数（Body Mass Index）；FPG：空腹血浆葡萄糖（fasting plasma glucose）；HOMA_IR：稳态模型评估（Homeostatic Model Assessment）；ANGPTL 6：血管生成素样蛋白6（angiopoietin-like protein 6）；DLK1：前脂肪细胞因子1（preadipocyte factor 1）；Nampt：烟酰胺磷酸核糖转移酶（nicotinamide phosphoribosyltransferase, visfatin）。