PREVALENCE OF URINARY TRACT INFECTIONS AMONG INDIVIDUALS WITH PRESUMPTIVE UTI ACCESSING HEALTHCARE IN SELECTED HEALTH FACILITIES IN ENUGU, NIGERIA

Urinary tract infection (UTI) is infection of the bladder, ureters, kidneys and/or Urethra, symptoms of which vary depending on its severity and the characteristics of an infected individual. This study examined the prevalence of UTI among individual with presumptive UTI accessing health care services in two health facilities in Enugu metropolis. Mid-stream urine samples were collected from 384 participants and analyzed bacteriologically using standard methods. The prevalence of UTI among the study participants was 34.6%., 133 out of 384 having positive bacteria urine test. Staphylococcus aureus (n=19), Escherichia coli (n=52), Klebsiella pneumoniae (n=45), Pseudomonas aeruginosa (n=12), Enterococcus faecalis (n=9) and Proteus mirabilis (n=8) were isolated as a single or mixed culture. Escherichia coli was the most implicated in the study followed by Klebsiella pneumoniae, Staphylococcus aureus, Pseudomonas aeruginosa, Enterococcus faecalis and Proteus mirabilis. Prevalence of UTI in females was 63.9% and 36.1% in males. The married (56.8%) and the singles (34.1%) recorded higher prevalence of UTI compared with the widow/widower (6.0%) and the divorced (3.1%). UTI was comparatively high (33.1%) among the age group 25 – 34 years and low (27.1%) in those >64 years. Civil servants and participants with tertiary level of education had UTI prevalence of 41.4% and 38.3% respectively. There was a significant difference in UTI based on sex (p=0.001) and age (p=0.02), but no significant difference based on marital status, occupation and educational level (p˃0.05). The prevalence of UTI in the study was high with both gram-positive and gram-negative bacteria implicated. Sex and age seem to play a significant role in UTI unlike marital status, educational level and occupation. Antibiotic susceptibility pattern of the UTI bacteria uropathogens should be investigated.

尿路感染（Urinary tract infection, UTI）是指膀胱、输尿管、肾脏及/或尿道发生的感染，其症状随感染严重程度及感染者个体特征而异。本研究针对埃努古都会区两家医疗机构中因疑似尿路感染就诊的人群，开展了尿路感染患病率调查。研究人员从384名受试者中采集中段尿样本，采用标准方法开展细菌学检测分析。本研究受试者的尿路感染患病率为34.6%，384人中共有133例尿液细菌检测呈阳性。本次分离得到的病原体包括：金黄色葡萄球菌（n=19）、大肠埃希菌（n=52）、肺炎克雷伯菌（n=45）、铜绿假单胞菌（n=12）、粪肠球菌（n=9）及奇异变形杆菌（n=8），分离形式涵盖单一菌培养与混合菌培养。本研究中致病率最高的病原体为大肠埃希菌，其次依次为肺炎克雷伯菌、金黄色葡萄球菌、铜绿假单胞菌、粪肠球菌及奇异变形杆菌。女性尿路感染患病率为63.9%，男性为36.1%。已婚人群（56.8%）与单身人群（34.1%）的尿路感染患病率高于丧偶人群（6.0%）及离异人群（3.1%）。25~34岁年龄组的尿路感染患病率相对较高（33.1%），而64岁以上人群患病率较低（27.1%）。公务员及受高等教育人群的尿路感染患病率分别为41.4%与38.3%。本研究显示，尿路感染患病率在性别（p=0.001）与年龄组（p=0.02）间存在显著差异，但在婚姻状况、职业及受教育水平间无显著差异（p>0.05）。本研究中尿路感染患病率较高，致病病原体涵盖革兰阳性菌与革兰阴性菌。与婚姻状况、受教育水平及职业不同，性别与年龄似乎对尿路感染的发生具有显著影响。后续应针对尿路感染致病菌的抗生素药敏谱开展进一步研究。

搜集汇总

背景与挑战

背景概述

该数据集总结了尼日利亚埃努古地区两家医疗机构中疑似尿路感染（UTI）个体的UTI患病率研究。研究基于384名参与者的尿液样本分析，发现UTI总体患病率为34.6%，女性患病率显著高于男性，且年龄和性别对UTI有显著影响，而婚姻状况、教育水平和职业则无显著差异。