This project aims to map the proximity interactome of SIGLEC-G in primary mouse MDMs using APEX2-mediated proximity labeling and quantitative mass spectrometry.
Primordial germ cell 7 (PGC7), a maternal factor essential for early development, plays a critical role in the regulation of DNA methylation, transcriptional repression, chromatin condensation, and ce
Cellular processes arise from the dynamic organization of proteins in networks of physical interactions. Mapping the complete network of biologically relevant protein-protein interactions, the interac