Data underlying the publication: Neuroprotective Effects of Everolimus via Regulation of Autophagy-Related Proteins in a Cerebral Ischemia-Reperfusion Rat Model

The data was collected from MCAO rats to evaluate the neuroprotection of everolimus. In excel file, the Longa’s neurological scale was applied to evaluate neurobehavioral deficit in ischemia/reperfusion-induced rats, and the ischemic infarct area of each section was calculated as infarct size. Besides, immunochemical staining of MCAO rats for mTOR and Beclin-1 expression was uploaded to observe the influence of everolimus on mTOR and Beclin-1. Besides, the data also included WB images of pPI3K, PI3K, pAkt, Akt, LC3-I, LC3-II. This study explored the effect of everolimus on the expression of PI3K, LC3, and Akt proteins and further clarified the regulatory mechanism of nerve cell autophagy against neural lesions.