ABSTRACT Introduction: Pulmonary artery denervation (PADN) can reduce the sympathetic nervous system (SNS) activity, reduce pulmonary artery pressure (PAP), and improve the quality of life in patients
Pathway depicting the effect of sildenafil treatment. Related treatment options that target components of the same pathway are included. Developed in collaboration with Werner Koopman, Alessandro Prig
Introduction: Pulmonary arterial hypertension (PAH) is a rare and progressive disease. Some patients treated with phosphodiesterase type 5 inhibitors (PDE-5is) fail to reach treatment goals. As a nove
This was a retrospective cohort study of 59 consecutive children (aged 2–18 years) with a diagnosis of severe PAH-CHD secondary to a simple shunt defect, who underwent surgical repair for CHD, with or
