The design of small molecules that inhibit disease-relevant proteins represents a longstanding challenge of medicinal chemistry. Here, we describe an approach for encoding this challengethe inhibitio
This study is to determine the metabolic pathways of selected plants by which the plants produce high value added metabolites and reproduce these pathways in the common yeast cell such that the yeast
Traditional bioproduct engineering focuses on pathway optimization, yet is often complicated by product inhibition, downstream consumption, and the toxicity of certain products. Here, we present the c
Figure. 2. Genome Mining Strategies for Natural Product Discovery: Genome mining approaches leverage DNA extraction, sequencing, and bioinformatics to uncover the biosynthetic potential of microorgani
