Multitargets compounds from literature

Name: Multitargets compounds from literature
Creator: Saldivar, Fernanda
Published: 2023-08-11T00:00:00+08:00

Figshare2023-08-11 更新2026-04-08 收录

多靶点药物

ADME-Tox性质预测

数据链接：

https://figshare.com/articles/dataset/Multitargets_compounds_from_literature/23929680/1 数据链接链接失效反馈

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资源简介：

91 multitarget compounds with reported <i>in vivo</i> activity in csv format. The database includes ADME-Tox properties calculated in ADMET.lab 2.0

提供机构：

Saldivar, Fernanda

创建时间：

2023-08-11

Drug discovery and computational strategies in the multitarget drugs era

多靶点药物

计算机辅助药物设计

The pharmaceutical industry is increasingly joining chemoinformatics in the search for the development of new drugs to be used in the treatment of diseases. These computational studies have the advant

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Discovery and In Vivo Proof of Concept of a Highly Potent Dual Inhibitor of Soluble Epoxide Hydrolase and Acetylcholinesterase for the Treatment of Alzheimer’s Disease

多靶点药物

阿尔茨海默病治疗

With innumerable clinical failures of target-specific drug candidates for multifactorial diseases, such as Alzheimer’s disease (AD), which remains inefficiently treated, the advent of multitarget drug

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Discovery of Novel Fedratinib-Based HDAC/JAK/BRD4 Triple Inhibitors with Remarkable Antitumor Activity against Triple Negative Breast Cancer

三阴性乳腺癌治疗

多靶点药物

Multitarget HDAC inhibitors capable of simultaneously blocking the BRD4-LIFR-JAK1-STAT3 signaling pathway hold great potential for the treatment of TNBC and other solid tumors. Herein, novel Fedratini

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Ex4-D-Ala bound to the glucagon-like peptide-1 receptor/g protein complex (conformer 2)

GPCR结构生物学

多靶点药物

Ex4-D-Ala bound to the glucagon-like peptide-1 receptor/g protein complex (conformer 2) Descriptor: Glucagon-like peptide 1 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2,

Protein Data Bank Japan2024-10-23 更新40

datasheet3_QSAR Modeling for Multi-Target Drug Discovery: Designing Simultaneous Inhibitors of Proteins in Diverse Pathogenic Parasites.pdf

多靶点药物

抗寄生虫药物设计

Parasitic diseases remain as unresolved health issues worldwide. While for some parasites the treatments involve drug combinations with serious side effects, for others, chemical therapies are ineffic

NIAID Data Ecosystem40

Multitargets compounds from literature

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