Treatment with commonly used antiretroviral drugs induces a type I/III interferon signature in the gut in the absence of HIV infection: Proteomics from MTN017

The purpose of this data set was to measure how the expression of proteins in rectal biopsies is affected by use of oral tenofovir disoproxil fumarate/emtricitabine for prevention of HIV infection. Proteins were measured by mass spectrometry from samples taken from the MTN-017 study at baseline and after two months of daily oral tenofovir disoproxil fumarate/emtricitabine. <br>In the raw_data tab, each row is a sample. There are several columns describing each sample and then many columns containing the expression level for each detected protein. Expression levels were adjusted for batch effects using ComBat. <br>In the protein_lookup tab, there is one row per protein detected, mapping from UniProt ID to gene symbol and Entrez Gene ID. <br>The complete methods and results are described here: https://doi.org/10.1101/701961