Profiling of gain and loss of DNA fragments in HHR comparing control SDR. Two analyses were performed; sample 1, SDR (male) vs HHR (male) and sample 2, SDR (female) vs HHR (female).
Short-read sequencing of the SPRET/EiJ mouse genome. For information on use of the data and the data release policy please see http://www.sanger.ac.uk/mousegenomes/datarelease.shtml
Itaconate is an immunoregulatory metabolite derived from the tricarboxylic acid cycle and exerts anti-inflammatory effect by activating the nuclear factor erythroid 2-related factor 2 (Nrf2) pathway.