官方服务：
资源简介：
DNase-seq in mESCs
应用场景：
创建时间：
2021-06-26
相关数据集
Oct4 cooperates with distinct ATP-dependent chromatin remodelers in naïve and primed pluripotent states in human [RNA-seq}
Understanding the molecular underpinnings of pluripotency is a prerequisite for optimal maintenance and application of embryonic stem cells (ESCs). While the protein-protein interactions of core pluri
干细胞与再生医学数据中心2022-02-20 更新90
Gene expression analysis of mESCs following short-term inhibition with PD032, CHIRON, EPZ6438 and GSK-J4 both individually and in combination.. Mus musculus
This experiment was designed to determine the extent of gene misregulation in mouse ESCs cultured for 24hrs in different base medias and treated with the indicated inhibitors. Overall design: Polyaden
NIAID Data Ecosystem50
Derivation of formative-like pluripotent stem cells from mammalian embryos [RNA-Seq]
Two phases of pluripotency, naïve and primed, have been captured in vitro and studied in details1. A third formative phase was recently proposed to exist between naïve and primed phases2. Formative
NIAID Data Ecosystem40
Genome-wide epigenome mapping in human induced pluripotent cells in WT and KMT2CKO cells. [ATAC-Seq]
KMT2C is a histone methyltransferase that mono-methylates lysine four at enhancer regions. This study compares the open and closed chromatin region between WT and KMT2C KO cells and further evaluates
NIAID Data Ecosystem70
Serum-based culture conditions provoke gene expression variability in mouse embryonic stem cells as revealed by single cell analysis. Mus musculus
Variation in gene expression is an important feature of mouse embryonic stem cells (ESCs). However, the mechanisms responsible for global gene expression variation in ESCs are not fully understood. We
NIAID Data Ecosystem40
