The RNA sequence of descending aorta (DA) in both amotl2ec+/ec+ and amotl2ec-/ec- mice

EC alignment and cytoskeletal reorganization in response to laminar blood flow is protective against inflammation. The lack of alignment of amotl2ec-/ec- EC in the aorta raised the question whether this was accompanied by a pro-inflammatory response. mRNA was therefore isolated from DAs in both amotl2ec+/ec+ (n = 3) and amotl2ec-/ec- (n = 5) mice and analysed by RNA-seq.