Ultrahigh-throughput LAP-MALDI MS analysis of peptides and an enzyme assay

As part of the PhD project 'Advancing liquid MALDI Ion Source Designs and Applications in Modern Biological Mass Spectrometry' funded by the University of Reading and Waters Corporation the possiblity for high-throughput analysis of biomolecules was investigated. Raw and processed data for liquid atmospheric-pressure matrix-assisted laser desorption/ionisation (LAP-MALDI) mass spectrometry analysis of peptides and enzyme assay at speeds greater than 20 samples/s using a hardware and software-modified Synapt G2-Si with a UV laser are presented. The deposited data relate to the research article 'Ultrahigh-throughput sample analysis using liquid atmospheric pressure matrix-assisted laser desorption/ionization mass spectrometry', 2022, Krenkel et al., https://doi.org/10.1021/acs.analchem.1c05614.