Additional file 7: of HIF prolyl hydroxylase inhibition protects skeletal muscle from eccentric contraction-induced injury

Table S4. Effect of daprodustat on serum protein changes pre- and 3 days post exercise. Excel file for SOMAscanÂŽ (SOMAlogic Inc.) aptamer-based proteome analysis of serum comparing baseline (pre-injury) and 72 h post-injury serum samples from Cohort 2 of the healthy volunteer study. Protein concentration data was log2 transformed and normalized using quantile normalization [44]. To determine differential expression, a linear model was fit [43] taking into account the treatment effect as well as the pair wise design (i.e., samples from the same individual before and after treatment). (PDF 1428 kb)