JMI_Gifford_WAT_CT_HU_vs_MRI_FSF: Replication data for: Correlations between quantitative fat-water magnetic resonance imaging and computed tomography in human subcutaneous white adipose tissue

The purpose of this work was to investigate whether the fat signal fraction (FSF) derived from quantitative fat-water MRI scans at 3.0 Tesla correlates to CT Hounsfield Units (HU) of the same tissue. These measures were acquired in the subcutaneous white adipose tissue (WAT) at the umbilical level of twenty-one healthy adult subjects. A moderate correlation exists between MRI and CT derived WAT values for all subjects, R2 = 0.54, p < 0.0001, with a slope of -2.6, (95% CI [-3.3, -1.8]), indicating that a decrease of 1 HU equals a mean increase of 0.38% FSF. This work demonstrates that FSF estimates obtained using quantitative fat-water MRI techniques correlate with CT HU values in subcutaneous WAT, and therefore, MRI based FSF could be used as an alternative to CT HU for assessing metabolic risk factors.本研究旨在探究3.0特斯拉场强下，通过定量脂肪水磁共振成像（quantitative fat-water MRI）获取的脂肪信号分数（fat signal fraction, FSF）是否与同一组织的CT亨氏单位（Hounsfield Units, HU）存在相关性。本研究采集了21名健康成年受试者脐部水平的皮下白色脂肪组织（subcutaneous white adipose tissue, WAT）的上述指标。所有受试者的MRI与CT测得的WAT指标间存在中等相关性，决定系数R²=0.54，p<0.0001，斜率为-2.6（95%置信区间CI：[-3.3, -1.8]），结果表明HU每降低1单位，FSF平均升高0.38%。本研究证实，通过定量脂肪水MRI技术获取的FSF估算值与皮下WAT的CT HU值具有相关性，因此基于MRI的FSF可作为CT HU的替代指标，用于评估代谢风险因素。