Dataset CAP

Molecular etiological profile of atypical bacterial pathogens, viruses and coinfections among infants and children with community acquired pneumonia admitted to a national hospital in Lima, Peru. Abstract Objetive: The main objective of this study was to detect the presence of 14 respiratory viruses and atypical bacteria (Mycoplasma pneumoniae, Chlamydia pneumoniae), via Polymerase Chain Reaction in patients under 18 years old hospitalized due to CAP from Lima, Peru. Results: Atypical pathogens were detected in 39.73% (58/146); viral etiologies in 35.62% (52/146) and coinfections in 18.49% (27/146). The most common etiological agent was M. pneumoniae (n=47), followed by C. pneumoniae (n=11). The most frequent respiratory viruses detected were: respiratory syncytial virus A (n= 35), influenza virus C (n= 21) and parainfluenza virus (n= 10). Viral-bacterial and bacterium-bacterium coinfections were found in 27 cases. In our study population, atypical bacteria (39.73%) were detected as frequently as respiratory viruses (35.62%). The presence of M. pneumoniae and C. pneumoniae should not be underestimated as they can be commonly isolated in Peruvian children with CAP.

秘鲁利马国家级医院收治的社区获得性肺炎（Community Acquired Pneumonia，CAP）婴幼儿的非典型细菌病原体、病毒及混合感染分子病原学特征。
摘要
研究目的：本研究旨在通过聚合酶链反应（Polymerase Chain Reaction，PCR），检测秘鲁利马18岁以下因社区获得性肺炎住院患者体内14种呼吸道病毒及非典型细菌（肺炎支原体（Mycoplasma pneumoniae）、肺炎衣原体（Chlamydia pneumoniae））的存在情况。
研究结果：非典型病原体检出率为39.73%（58/146），病毒病原学检出率为35.62%（52/146），混合感染检出率为18.49%（27/146）。最常见的致病病原为肺炎支原体（n=47），其次为肺炎衣原体（n=11）。检出频率最高的呼吸道病毒依次为：呼吸道合胞病毒A型（n=35）、丙型流感病毒（n=21）及副流感病毒（n=10）。共发现27例病毒-细菌及细菌-细菌混合感染病例。在本研究人群中，非典型细菌检出率（39.73%）与呼吸道病毒检出率（35.62%）相当。肺炎支原体与肺炎衣原体的存在不应被低估，因其在秘鲁社区获得性肺炎患儿中可被普遍检出。